PROMOTE will train young and ambitious scientists to combat prostate cancer (PCa) by offering them a comprehensive and inter-sectoral training to change our view on the disease initiation and progression. Thus, young scientists will focus on delivering currently missing knowledge on the molecular pathophysiology of prostate cancer progression, setting up a stage for non-invasive diagnostic and stratification biomarkers for discriminating early stages of prostate cancer, but also molecularly driven novel anti-cancer therapies.